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Product Detail
Dibucaine HCL
Detail

Dibucaine HCL

CAS: 61-12-1

EINECS No.: 200-498-1

MF:C20H30ClN3O2

MW:379.92

Storage conditions: Refrigerator


Appearance:White crystal powder


Solubility: soluble in 0.5 parts water, soluble in ethanol, acetone and chloroform, slightly soluble inbenzene, toluene, ethyl acetate and hot, insoluble in ether and oils. 1:20 litmus weakly alkaline aqueous solution


Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction


Injection of anesthetic drugs is 15 times the strength of procaine, toxicity is also 15 times. Slow onset, about 15min, but the duration is 3 times of procaine. Local irritation, strong penetrating power. Used for surface anesthesia, anesthesia or epidural anesthesia.