Hangzhou Fuluo Biological Technology Co.,Ltd. 
Product Detail


CAS No.: 159752-10-0

Molecular Formula: C27H36N4O5S.CH4O3S

Formula Weight: 624.776  


MK-0677 is an orally active nonpeptide growth hormone (GH) secretagogue. Ibutamoren mesylate (MK-0677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor. MK-677is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. Ibutamoren mesylate (MK-0677) also alters metabolism of body fat and so may have application in the treatment of obesity.


MK-677 is a nootropic drug derived from piracetam, and is more potent (i.e. lower dosage is used). It belongs to the racetam family of nootropics. MK-677 was developed based on Piracetam, and is 8-30 times stronger than Piracetam. It goes by the trade name Neupramir or Pramistar.